PharmaPure® Low Spallation Pump Tubing
PharmaPure® is an ultra-pure pump tubing with exceptional pump life. Download the new white paper here.
PharmaPure® is a premium, low spallation, biologically compatible peristaltic pump tube developed especially for pharmaceutical, biotechnology, and laboratory applications. This tubing meets the challenges of providing unsurpassed pump life with ultra-low particulate spallation and very low permeability. The superior flex life characteristics of PharmaPure reduce production downtime due to pump tubing failures. In addition, PharmaPure’s low permeability is ideal for protecting sensitive cell cultures, fermentation, separation, purification, process monitoring, and sterile filling.
Features & Benefits
- Ultra-low particulate spallation
- Outlasts silicone tubing in peristaltic pumps by up to 30 times
- Provides an excellent gas barrier with very low permeability
- Autoclavable and sterilizable
- Custom molding and design capabilities
- Meets the requirements of USP, Biological Test for Plastics, Class VI
- Documented biocompatibility – validation summary available upon request
Applications
- Media Process Systems
- Vaccine Manufacturing
- Bioreactor Process Lines
- Sterile Filling
- Diagnostic Test Products
- Production Filtration and Fermentation
- Shear-Sensitive Fluid Transfer
Application Impact
Critical Applications Rely on PharmaPure® Purity
Low spallation tubing is essential across the most sensitive modalities in the biopharma industry:
| Application | Why Low Spallation Matters | Modality Focus |
|---|---|---|
| Sterile Fill-Finish | Protects the final drug product after filtration, directly impacting patient safety and regulatory compliance. | Aseptic Processing |
| Cell & Gene Therapies (CGT) | Prevents contaminants from impacting sensitive cell viability, growth, and function in bioreactors and media transfer. | High-Value/Low-Volume Products |
| Separation and Purification | Prevents the fouling of costly chromatography resins and TFF membranes, maintaining process efficiency. | Peristaltic Pumping |
| Process Monitoring | Ensures samples accurately reflect fluid purity without contamination from the tubing itself. | Single-Use Systems (SUS) |
Resource Center
Gated Documentation
Product Information
Product Documents
The PharmaPure® Purity and Stability Advantage
Proven stability and ultra-low spallation, even after rigorous sterilization.
Your high-value applications demand a tubing solution that won't compromise purity or performance - especially after sterilization. Our latest research confirms that PharmaPure® tubing delivers on both fronts. We've proven its mechanical and chemical stability after exposure to autoclaving and high-dose gamma irradiation (up to 50 kGy) while demonstrating a superior commitment to ultra-low particle shedding (spallation).
The Low Spallation Advantage
Particles shed from tubing during pumping are a major threat to your drug substance. PharmaPure® is engineered to minimize this risk:
New White Paper - PharmaPure® Tubing Performance: Effects of Gamma Irradiation and Autoclaving
PharmaPure® tubing maintains mechanical integrity even at elevated sterilization levels:
Exceptional Pump Life
Gamma Stability
Mechanical Integrity
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