Visit us on Google+ Follow Saint-Gobain Life Sciences on Twitter Follow Saint-Gobain Life Sciences on LinkedIn Follow Saint-Gobain Life Sciences on YouTube
Case Studies
> Buffer Feed (Chromatography)
> Buffer Preparation (Liquid – Liquid Mixing)
> Bulk Drug Substance Fluid Transfer
> Cell Clarification (Post Centrifugation)
> Cell Culture Media Charge
> Cell Culture Sampling (Bags)
> Cell Culture Sampling (Bottles)
> Cold Storage / Transport
> Final Fill (C-Flex®)
> Final Fill (Sani-Tech® Ultra) #1
> Final Fill (Sani-Tech® Ultra) #2
> High Pressure Filtration
Related Products
> C-Flex® 374 Tubing
> BarbLock® Retainers
> PureFit ® SIB® Connectors
> Sampling Bags
Cell Culture Sampling (Bags) << Case Studies

The Challenge
A process engineer from an animal healthcare manufacturer faced contamination risks due to their open environment sampling procedure and desired a sterile closed system for microbiology analysis during cell culture. If cell culture was falsely identified as contaminated due to a poor sampling process then batch loss would result.

The Saint-Gobain Collaborative Design Services' Solution
The customer shared their current cell culture sampling requirements for their existing bioreactors with our Design Services Team. The goal was to develop a single-use system that supported (4) – (12) sample collections plus (1) effluent bag during cell culture. 150ml Saint-Gobain Bioprocess Bags constructed of 7mil multi-layer film (LDPE/EVOH/Nylon), C-Flex® 374 heat sealable and weldable tubing, Pure-Fit® SIB® Connectors and needle-free sample ports were assembled into a manifold assembly. Prototypes were built and confirmation of the cell culture sampling process efficiency resulted. The final product was delivered to the customer gamma sterilized with a sterility assurance level of (SAL) of 10-6.

Customer Experience
This newly implemented single-use sampling system has eliminated the customer’s contamination false positives as experienced with previous sampling process.

C-Flex® / Pure-Fit® / BarbLock® / SIB® are registered trademarks of Saint-Gobain Performance Plastics
About Us | Brand Name | Products | Capabilities | Literature | Case Studies | News & Events | Contact | Sitemap
Laboratory Products | Medical Products | Cell Therapy | Performance Plastics
Terms of Use | Privacy Statement | Saint-Gobain North America | Doing Business with SGNA | CATSCA Certification
© Saint-Gobain Performance Plastics, 2018. All rights reserved.